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Wednesday, July 15, 2020 | History

4 edition of Heterogeneity of mononuclear phagocytes found in the catalog.

Heterogeneity of mononuclear phagocytes

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  • 27 Currently reading

Published by Academic Press in London, New York .
Written in English

    Subjects:
  • Monocytes -- Congresses.,
  • Phagocytosis -- Congresses.

  • Edition Notes

    Statementedited by Othmar Förster, Maurice Landy.
    ContributionsFörster, Othmar., Landy, Maurice.
    Classifications
    LC ClassificationsQP95.7 .H47
    The Physical Object
    Paginationxxviii, 538 p. :
    Number of Pages538
    ID Numbers
    Open LibraryOL3788879M
    ISBN 100122623606
    LC Control Number81066367

    Helena Todorov's 14 research works with citations and reads, including: Open Source ImmGen: network perspective on metabolic diversity among mononuclear phagocytes. The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3 Immunology. Mar;54(3) Authors C D Dijkstra, E A Döpp, P Joling, G Kraal. PMID.

    Differential effects of LPS, IFN-gamma and TNF alpha on the secretion of lysozyme by individual human mononuclear phagocytes: relationship to cell maturity. Immunology. Mar; 69 (3)– [PMC free article] Dimitriu-Bona A, Burmester GR, Waters SJ, Winchester RJ. Human mononuclear phagocyte differentiation antigens. I. Background and aims: Crohn's disease [CD] and ulcerative colitis [UC] are distinct forms of inflammatory bowel disease. Heterogeneity of HLA-DR+SIRPα + mononuclear phagocytes [MNPs], including macrophages [MΦ], monocyte-derived [Mono] cells, and dendritic cells [DCs], was reported in gut tissue but not yet investigated in mesenteric lymph nodes [MLNs] of IBD patients.

    The human liver contains specialized subsets of mononuclear phagocytes (MNPs) and T cells, but whether these have definitive features of tissue residence (long-term retention, lack of egress) and/or can be replenished from the circulation remains unclear.   Phenotypic heterogeneity of monkey mononuclear phagocytes in blood. Within the blood, the mononuclear phagocyte system is represented by monocytes, which can be identified by flow cytometry as cells within a “gate” of high forward‐scatter and intermediate side‐scatter.


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Heterogeneity of mononuclear phagocytes Download PDF EPUB FB2

Therefore, the main subjects will be the mononuclear phagocyte system as a whole and the heterogeneous features of the various members of the system expressed both phenotypically and functionally. Finally, we will discuss various models that may explain how mononuclear phagocyte heterogeneity is generated (see also Chapter 3, this volume).Cited by: The mononuclear phagocyte system: a new classification of macrophages, monocytes, and their precursor cells.

Bull World Health Organ. ; 46 (6)– [PMC free article] Veerman AJ. On the interdigitating cells in the thymus-dependent area of the rat spleen: a relation between the mononuclear phagocyte system and by: IV. Tissue-bound interstitial mononuclear phagocytes. Others have previously shown that the lung tissue microenvironment determines the function and distribution of discrete subsets of mononuclear phagocytes in rodents [].In addition, alveolar macrophages transition from blood monocytes but they require an obligate intermediate stage found within the lung interstitium [].Cited by: Heterogeneity of mononuclear phagocytes.

[Othmar Förster; Maurice Landy;] Home. WorldCat Home About WorldCat Help. Search. Search for Library Items Search for Lists Search for Book: All Authors / Contributors: Othmar Förster; Maurice Landy. Find more information about: ISBN:   The number of subpopulations of mononuclear phagocytes one can define is an exponential function of the number of markers examined 19; the heterogeneity is essentially infinite because each gene Cited by:   The fact that the plasticity of mononuclear phagocytes determines whether they promote or prevent disease is well supported by previous work demonstrating that macrophage activation and polarization determines angiogenic fate in the retina (Kelly et al.,Lin et.

Human Heterogeneity of mononuclear phagocytes book phagocytes comprise phenotypically and functionally overlapping subsets of dendritic cells (DCs) and monocytes, but the extent of their heterogeneity and distinct markers for subset identification remains elusive.

By integrating high-dimensional single-cell protein and RNA expression data, we identified distinct markers to. Introduction. Mononuclear phagocytes (MNPs) comprise a heterogeneous population of cells historically assigned to subsets based on their phenotype, ontogeny, transcriptomic profiles, and specialized functions (Guilliams et al., ).MNPs comprise dendritic cell (DC) and monocyte subsets in the blood and tissues, as well as macrophages and monocyte-derived cells (MCs) in tissues (Dutertre.

Heterogeneity of 5′-nucleotidase activity and wheat-germ agglutinin binding in mononuclear phagocytes L. Ginsel, R. de Water, J. van der Meer, W. Daems Pages Mononuclear phagocyte system, also called macrophage system or reticuloendothelial system, class of cells that occur in widely separated parts of the human body and that have in common the property of phagocytosis, whereby the cells engulf and destroy bacteria, viruses, and other foreign substances and ingest worn-out or abnormal body pathologist Karl Albert Ludwig Aschoff.

Robert Sullivan, Clémence Belleannée, in Encyclopedia of Reproduction (Second Edition), Mononuclear phagocytes. Mononuclear phagocytes comprise dendritic cells and macrophages that are in close proximity to the epididymal epithelium.

These cells were discovered recently and have been characterized all along epididymides from transgenic mouse models by using different immune cell. Dijkstra C.D., Döpp E.A., Joling P., Kraal G. () The Heterogeneity of Mononuclear Phagocytes in Lymphoid Organs: Distinct Macrophage Subpopulations in Rat Recognized by Monoclonal Antibodies ED1, ED2 and ED3.

Mononuclear phagocytes have been recognized for their role in antimicrobial immunity since their initial description. Categorized as monocytes, macrophages, and dendritic cells (DC), the mononuclear phagocyte system is characterized by marked heterogeneity and incompletely defined cellular lineages.

In the bone marrow compartment, the. The number of subpopulations of mononuclear phagocytes one can define is an exponential function of the number of markers examined 19; the heterogeneity is essentially infinite because each gene has its own intrinsic probability of being expressed It is clear that the definition of DCs has changed with time.

Van der Meer JWM, Beelen RHJ, Fluitsma DM, Van Furth R: Ultrastructure of mononuclear phagocytes developing in liquid bone marrow cultures. A study on peroxidatic activity. J Exp Med,17– PubMed CrossRef Google Scholar. Antigenic differences were also detected between mononuclear phagocytes present at different sites, different stages of differentiation, and likely different states of activation.

These studies provide evidence of major antigenic differences between various populations of human mononuclear phagocytes.

David B. Lewis, in Fetal and Neonatal Physiology (Third Edition), Mononuclear Phagocytes and Inducible Nitric Oxide Synthase. Mononuclear phagocytes are widely distributed in the tissues as macrophages and are likely to play an important role in the local containment of HSV infection until adaptive immune responses can come into play.

After intraperitoneal injection of HSV or murine CMV. In immunology, the mononuclear phagocyte system or mononuclear phagocytic system (MPS) also known as the reticuloendothelial system or macrophage system is a part of the immune system that consists of the phagocytic cells located in reticular connective cells are primarily monocytes and macrophages, and they accumulate in lymph nodes and the spleen.

Cells of the mononuclear phagocyte system (MPS) are found in large numbers in every organ of the body, where they contribute to innate and acquired immunity and homeostasis. This review considers. Monocytes are innate immune cells of the mononuclear phagocyte system that have emerged as important regulators of cancer development and progression.

Our understanding of monocytes has advanced from viewing these cells as a homogenous population to a heterogeneous system of cells that display diverse responses to different stimuli. Immunity Article The Heterogeneity of Ly6Chi Monocytes Controls Their Differentiation into iNOS+ Macrophages or Monocyte-Derived Dendritic Cells Shinelle Menezes,1,2,3 Daisy Melandri,1,2,3 Giorgio Anselmi,1,2,3 Thibaut Perchet,4 Jakob Loschko,5 Juan Dubrot,6 Rajen Patel,1,2 3 Emmanuel L.

Gautier,7 Ste´phanie Hugues,6 M. Paula Longhi,8 Jake Y. Henry,9 Sergio A. Quezada,9.Ralph Snyderman, in Methods for Studying Mononuclear Phagocytes, I INTRODUCTION. Mononuclear phagocytes are motile cells that are able to sense and migrate along gradients of certain chemical substances.

The ability of phagocytes to migrate unidirectionally in response to chemical signals may be an important mechanism by which they accumulate at sites of inflammation.

Chronic obstructive pulmonary disease (COPD) is a disease defined by an aberrant inflammatory response to inhaled cigarette smoke and other noxious particles. The factors triggered in the lungs that drive inflammation and lung tissue destruction are not fully understood, but mononuclear phagocytes play a central role by releasing mediators that pro.